Disease: Hyperhomocysteinemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
THBD P07204 thrombomodulin 5.4E-02 0.457 0.769
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MIR143 microRNA 143 0.462 0.885
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846